Physiospect Diagnostics

Mammary Gland Cancer

NLS Diagnosis Of Affected Regional Lymph Nodes
O.P. Dergatch, Y.A. Somov,

M:A: Kolensnikov, L:V: Chernyshov

Mammary gland cancer is one of the most common women’s oncologic diseases. Its annual growth rate in the developed countries is about 3%. In addition, this pathology proves to be the primary cause of mortality among females affected by oncologic deseases. The tactics of treatment and disease prognosis largely depend on the presence or absence of any regional metastases. In this connection the problem of competent diagnosis of affected regional lymph nodes becomes especially pertinent. With that end in view a number of methods have been used, from physical to hardware-based examinations. However, in 40% of the patients metastatic leasion of the lymph nodes in the axillary are is not determined clinically and false positive data were observed in 25% of cases. Instrumental diagnosis methods do not have a rich informational content either. The NLS investigation of regional lymph nodes has been more ectensively used lately.


Subject and methods of investigation
We have examined regional lymph nodes by means of a device NLS with a 4.9 GHz nonlinear trigger sensor in 25 patients affected by mammary gland cancer in Phases I-III. The obtained data were compared with the results of histological investigation of the macro-preparations removed during surgery.


Investigation results
Of 25 patients examined prior to surgery as many as 1-3 affected lymph nodes were in detected in 20 patients. The derived results were practically fully confirmed histological investigation of the macro-preparations removed during surgery. Only in one case NLS ananlysis di not detect affected nodes which we account for their small size.
During the NLS investigation the metastatic lymph nodes were found to have pathological changes with quite a high degree of intensity. Flandler’s scale indicated 5-6 points in 80% of cases.
The fact that organo-saving surgery and in some cases tuorectomy are being more and more extensively used these days make the NLS investigation even more important. Our own practical experience can confirm that. Patient B. 63 years old was admitted to the clinic with refard to right mammary gland cancer in its early phse IIa, after and ischemic stroke in combination with ischemic heart disease and hypertension III. Palpation did not detect any lymph node enlargement. The NLS investigation did not detect metastases-affect lymph nodes with allowed a tumorectomy for this patient at a low hazard to life.

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